Jay V. Solnick, M.D., Ph.D.
Center for Comparative Medicine
Davis Campus

Bacterial pathogenesis, bacterial and host gene transcription in the non-human primate model of Helicobacter pylori.

Lab Page: https://ccm.ucdavis.edu/faculty/solnick/

Moonens, K, Gideonsson, P, Subedi, S, Bugaytsova, J, Romaõ, E, Mendez, M, Nordén, J., Fallah, M, Rakhimova, L., Shevtsova, A, Lahmann, M., Castaldo, G, Brännström, K, Coppens, F, Lo, AW, Ny, T, Solnick, JV, Vandenbussche, G, Oscarson, S, Hammarström, L, Arnqvist, A, Berg, D, Muyldermans, S, Borén, T, Remut, H. Structural Insight in Adaptive and Redox-sensitive ABO Glycan Binding by Helicobacter pylori. Cell Host Microbe, 2016, 19:55-66.

Ozcan S, Barkauskas DA, Renee Ruhaak L, Torres J, Cooke CL, An HJ, Hua S, Williams CC, Dimapasoc LM, Han Kim J, Camorlinga-Ponce M, Rocke D, Lebrilla CB, Solnick JV. Serum glycan signatures of gastric cancer. Cancer Prev Res, 2014, 7:226-35.

Moore ME, Lam A, Bhatnagar S, Solnick JV. Environmental determinants of transformation efficiency in Helicobacter pylori. J Bacteriol. 2014,196:337-44.

Linz, B, Windsor, HM, McGraw, JJ ,Hansen, LM , Gajewski, JP,Tomsho,LP, Hake,CM, Solnick, JV,  Schuster, SC, and Marshall, BJ. A mutation burst during the acute phase of Helicobacter pylori infection in humans and rhesus macaques.  Nat Commun. 2014, 5:4165

Barrozo, RM, Cooke, CL, Hansen, LM, Lam, AM, Gaddy, JA, Johnson, EM, Cariaga, TA, Suarez, G, Peek, RM Jr, Cover, TL, and Solnick, JV. Functional plasticity in the type IV secretion system of Helicobacter pylori. PLoS Pathogens, 2013, Feb;9(2):e1003189

Martin ME, Bhatnagar S, George MD, Paster BJ, Canfield DR, Eisen JA, Solnick, JV. The impact of Helicobacter pylori infection on the gastric microbiota of the rhesus macaque. PLoS One. 2013 Oct 8;8(10):e76375.

Terio, KA, Munson, L, Marker, L, Aldridge, BM, and Solnick, JV. Comparison of Helicobacter spp. in cheetahs (Acinonyx jubatus) with and without gastritis. J Clin Microbiol, 2005, 43: 229-234.

O’Rourke, JL, Solnick, JV, Neilan, BA, Seidel, K, Hayter, R, Hansen, LM, and Lee, A. Description of "Candidatus Helicobacter heilmannii" based on DNA sequence analysis of 16S rDNA and urease genes. Int J Syst Evol Microbiol, 2004, 54: 2203-2211.

Ayala, G, Chihu, L, Perales, G., Fierros-Zarate, G, Hansen, LM, Solnick, JV, and Sanchez, J. Quantitation of Helicobacter pylori cytotoxin mRNA by real-time RT-PCR shows a wide expression range that does not correlate with promoter sequences. Microb Pathogen, 2004, 37: 163-167.

Huff JL, Hansen, LM, and Solnick, JV. A gastric transcription profile of Heliocbacter pylori infection in the rhesus macaque. Infect Immun, 2004, 72: 5216-5226.

Boonjakuakul, JK, Syvanen, M, Suryaprasad, A, Bowlus, C, and Solnick, JV.  A transcription profile of Helicobacter pylori in the human stomach reflects its physiology in vivo. J Infect Dis, 2004, 190: 946-956.

Solnick, JV, Hansen, LM, Salama, NR, Boonjakuakul, JK, and Syvanen, M. Modification of Helicobacter pylori outer membrane protein expression during experimental infection of rhesus macaques. Proc Natl Acad Sci USA, 2004, 101: 2106-2111.

Solnick, JV, Chang, K, Canfield, DR and Parsonnet. Natural acquisition of Helicobacter pylori in newborn rhesus macaques. J. Clin. Microbial. 2003, 41: 5511-16.

Dandekar, S., Reay E, Taylor, EM, and Solnick, JV. Apoptosis of gastric lymphocytes in Helicobacter pylori-infected rhesus macaques. Dig Dis Sci, 2003, 48: 1073-80.

Solnick, JV. Clinical significance of Helicobacter species other than H. pylori. Clin Infect Dis, 2003, 36:349-54.

Fernandez, KR, Hansen, LR, Vandamme, P, Beaman, BL., and Solnick, JV. Captive rhesus monkeys are commonly infected with Helicobacter cinaedi. J Clin Microbiol, 2002, 40: 1908-12.

Solnick JV, Hansen LM, Canfield DR. The [14]-C Urea Breath Test is Not Sensitive for Detection of Acute Helicobacter pylori Infection in Rhesus Monkeys (Macaca mulatta), 2002, 47:298-303