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Department of Neurology

Department of Neurology

Faculty | Professors




Multiple sclerosis 

Myasthenia gravis and Lambert Eaton Syndrome


To see if Mark Agius is accepting new patients, or for assistance finding a UC Davis doctor, please call (800) 2-UC DAVIS.


Mark Agius, M.D.

Mark A. Agius, M.D.

Specialty: Neurology

Lawrence J. Ellison Ambulatory Care Center
4860 Y St., Suite 0100
Sacramento, CA 95817
(916) 734-3588

Clinical & Research Interests

Mark A. Agius' clinical interests include pathogenesis of autoimmune disease of the nervous system.


University of Malta Medical School
M.D. 1977


Boston University School of Medicine
Boston, Massachusetts
Neurology/Internal Medicine


University of Chicago
Chicago, Illinois

Board Certifications

American Board of Neurology and Psychiatry, 1985

Professional Memberships

American Academy of Neurology
Mountain Valley California Chapter of the National Multiple Sclerosis Society
National Myasthenia Gravis Foundation of America, Medical Advisory Board
Royal College of Physicians (UK)
Royal College of Physicians and Surgeons of Canada
Royal College of Physicians and Surgeons of Glasgow
Western Society for Clinical Investigation


Select Recent Publications

Kim, S., Richman, D.P., and Agius, M.A. Limited applicability of Barkhof's MRI criteria in distinguishing multiple sclerosis from diseases mimicking multiple sclerosis. AAN, April 13th, 2005 (platform presentation, resident presentation). S26.006.


Zhang, L, Apperson M, Coffey, S., Agius, M., Nowicki, S., Tartaglia, N.R., Ono, M., Cook, K., Yuhas, J., Barbato, I., Harris, S., Gane, L., Tassone, F., Hessl, D., Cordeiro, L., Brungerg, J. Hall, D., Leehey, M., Hagerman, R. Clinical and MRI characteristics in females carrying the FMR1 premutation. AAN, April 12th, 2005. P02.052


O'Connor, P.W., Goodman, A., Willmer-Hulme, A.J., Libonati, M.A., Metz L., Murray R.S., Sheremata, W.A., Vollmer, T.L., Stone, L.A., Natalizumab Multiple Sclerosis Trial Group2. Randomized multicenter trial of natalizumab in acute MS relapses: clinical and MRI effects. Neurology 62(11):2038-43. 2004


Wolinsky, J., PROMiSe Trial Study Group3. The PROMiSe trial: baseline data review and progress report. Mult Scler. 2004 Jun;10 Suppl 1:S65-71; discussion S71-2.


Narayana PA, Wolinsky JS, Rao SB, He R, Mehta M; PROMiSe Trial MRSI Group3. Multicentre proton magnetic resonance spectroscopy imaging of primary progressive multiple sclerosis. Mult Scler. 2004 Jun;10 Suppl 1:S73-8.


Vollmer, T.L., Phillips, J.T., Goodman, A.D., Agius, M.A., Libonati, M.A., Giacchino, J.L., Grundy, J.S. An open-label safety and drug interaction study of natalizumab (Antegren) in combination with interferon-beta (Avonex) in patients with multiple sclerosis. Multiple Sclerosis, 10(6):510-520, 2004.


Rizvi, S.A., Agius, M.A. Current approved options for treating patients with multiple sclerosis. Neurology. 2004 Dec 28;63(12 Suppl 6):S8-14.


Cohen, B.A., Khan O., Jeffery, D.R., Bashir, K., Rizvi, S.A., Fox, E.J., Agius, M., Bashir, R., Collins, T.E., Herndon, R., Kinkel, P., Mikol, D.D., Picone, M.A., Rivera, V., Tornatore, C., Zwibel, H. Identifying and treating patients with suboptimal responses. Neurology. 2004. Dec 28:63(12 Suppl. 6):S33-40.


Agius, M.A. Conference lecturer: Immunological aspects of myasthenia gravis and related disorders, International Myasthenia Gravis Symposium, Myasthenia Gravis Foundation of Argentina, Ministero de Salud de la Nacion, Facultad de Medicina - Universidad de Buenos Aires, Buenos Aires, Argentina, May 20-21, 2004.