UC Davis research news releases
January 3, 2018
In a commentary published today in the New England Journal of Medicine, UC Davis researcher William Murphy expressed cautious optimism about efforts to genetically engineer hematopoietic stem cells (HSCs) to temporarily resist cell death during transplantation. While these gene therapy approaches could dramatically improve patient outcomes, Murphy argues that their risks must be carefully studied in diverse animal models.
December 28, 2017
Ophthalmologists’ use of electronic health records (EHR) systems for storing and accessing patients’ medical histories more than doubled between 2006 and 2016, while their perceptions of financial and clinical productivity following EHR implementation declined, a study published today in JAMA Ophthalmology shows.
December 21, 2017
A team of UC Davis investigators has been awarded a $1.2 million grant to examine a common virus and its effects on immune system function after stem cell transplantation.
December 19, 2017
Human and veterinary researchers at UC Davis and other institutions have shown that enhanced natural killer (NK) immune cells, combined with radiation therapy, can be effective against spontaneous osteosarcoma (bone cancer) in dogs. The research showed these NK cells homed in on cancer and reduced metastasis in the treated dogs, offering a potential immunotherapy against solid tumors. The study was published today in the Journal for Immunotherapy of Cancer.
December 14, 2017
A study assessing the impact of medical marijuana laws (MML) on adolescent substance use has found decreased use of all substances among 8th graders, no change among 10th graders and increased non-medical use of prescription opioids and cigarette use among 12th graders, following MML enactment.
December 14, 2017
About half of new moms in California, including those with diabetes, do not receive critical follow-up care within three months after giving birth, a new study published in the December issue of the journal Contraception shows.
December 4, 2017
A microscope using ultraviolet light to illuminate samples enables pathologists to assess high-resolution images of biopsies and other fresh tissue samples for disease within minutes, without requiring the time-consuming preparation of conventional slides or destroying the tissue.
Statewide survey finds physicians, pharmacists comply with prescription drug monitoring registration. Next step: increase use
November 29, 2017
A state law that funded upgrades to California’s prescription drug monitoring program and mandated physicians, pharmacists and controlled substance prescribers to register by July 2016 significantly increased registration rates, a new survey of 1,904 California physicians and pharmacists conducted by the UC Davis Violence Prevention Program has found.
November 27, 2017
Patients who ask for specialist referrals, laboratory tests or certain medications and don’t get them tend to be less satisfied with their doctors than those whose requests are fulfilled, new research from UC Davis Health shows. Based on the results, the study authors recommend communications training for physicians that fosters positive experiences for patients without agreeing to all requests for particular diagnostics or treatments.
November 27, 2017
A large, multi-center, international study to assess the long-term benefits of glucocorticoid treatment for Duchenne muscular dystrophy (DMD) concludes that it does preserve muscle strength and function as well as reduce the risk of death for patients.
November 21, 2017
The medical school interview – a key determinant in the admissions process and, ultimately, in the physician workforce – appears to skew for or against applicants depending on their age, gender and self-identified disadvantaged socioeconomic status.
November 20, 2017
UC Davis MIND Institute esearchers have shown in a mouse model that an elevated maternal immune response changes the epigenetic landscape in offspring’s microglia, immune cells found in the brain and spinal cord. These changes affect genes associated with immune signaling and neural development, some of which have been implicated in autism spectrum disorder (ASD). The study was published online in the journal Glia.
November 17, 2017
Giving bad news is never easy, especially when it’s life or death. But when an oncologist delivers a poor prognosis to a cancer patient, does it harm their relationship? Some research studies have suggested it can.
November 7, 2017
For many, breast cancer is more than just a disease – it’s personal. One in eight women will be diagnosed with breast cancer at some point in their lives. But through new discoveries at the genetic level, the personal nature of cancer will eventually be what helps to beat it.
October 25, 2017
Participating in a brief intervention delivered by their peers in community settings can help reduce smoking among youth and young adults, a new study from a team of tobacco-cessation researchers shows.
October 23, 2017
Research conducted in mice at the UC Davis MIND Institute suggests that a drug treatment can reverse cognitive deficits and social abnormalities in a rare genetic disorder, 16p11.2 deletion syndrome, which includes symptoms of intellectual disability and autism spectrum disorder, among others. Results of parallel studies conducted at the MIND and at the Massachusetts Institute of Technology Picower Institute for Learning and Memory appear in the latest issue of the journal Neuropsychopharmacology.
October 20, 2017
UC Davis has received its first National Cancer Institute (NCI) Moonshot grant ̶ $2.5 million over five years ̶ to explore immunotherapy treatments for dogs who develop melanoma and osteosarcoma and that may one day benefit humans, as well.
October 19, 2017
Members of the UC Davis Comprehensive Cancer Center lung cancer treatment team will present at WCLC 2017, a one-day conference on Saturday, Nov. 11, from 7 a.m. to 4 p.m. in San Francisco. Presenters will share the latest lung cancer and other thoracic malignancy advances highlighted at the recent 18th Annual World Conference on Lung Cancer in Japan.
October 9, 2017
Of the three states that recently expanded comprehensive background check (CBC) policies to include all gun transfers, including those among private parties, only Delaware showed an overall increase in firearm background checks. Washington and Colorado had no changes, which the study authors say suggests that compliance and enforcement were incomplete.
October 6, 2017
Assistant Professor Sean Collins, Department of Microbiology and Molecular Genetics, has received a $1.5 million award from the National Institutes of Health to advance the development of “smart” immune cells for therapies to treat cancer and other diseases. The five-year NIH Director’s New Innovator Award aims to provide new insight into how to engineer immune cells to control their recruitment and response to tumors.
September 28, 2017
The California Institute for Regenerative Medicine today awarded a nearly $8 million grant to University of California, Davis, stem cell researchers to launch a special clinical trials program in Sacramento to accelerate the therapeutic development and delivery of stem cell therapies in human patients.
September 27, 2017
UC Davis researchers, led by Julie Sutcliffe, have received a $3.3 million grant from the National Institutes of Health to advance efforts to diagnose pancreatic cancer before it spreads.
September 25, 2017
How do fire-suppression chemicals and pesticides affect wildfire smoke and the health of those who breathe it? UC Davis graduate students discovered that this question cannot be answered based on current scientific evidence and, in a review published in Current Topics in Toxicology, they recommend more studies on the compounds in wildfire smoke.
September 7, 2017
The UC Davis MIND Institute has been awarded a 5-year, $12 million Autism Centers of Excellence (ACE) grant, one of five in the nation, to create a “Center for the Development of Phenotype-based Treatments of Autism Spectrum Disorder.”
August 30, 2017
UC Davis stem cell scientist Paul Knoepfler has been awarded a second $250,000 grant for glioma research from an organization begun 15 years ago by a 5-year-old girl with a deadly form of childhood cancer.
August 24, 2017
A pair of English bulldog puppies are the first patients to be successfully treated with a unique therapy — a combination of surgery and stem cells — developed at the University of California, Davis, to help preserve lower-limb function in children with spina bifida.
August 18, 2017
UC Davis researchers have shown that radiation therapy before surgery improves overall survival for patients with soft tissue sarcomas. This pre-surgical, or neoadjuvant, radiotherapy allows surgeons to get better margins around tumors and remove even microscopic cancer tissue more often. The study was published recently in the Annals of Surgical Oncology.
August 18, 2017
A review of kidney cancer in California from 1988 through 2013 by the UC Davis Institute for Population Health Improvement (IPHI) has concluded that the high incidence of small tumors and early-stage disease observed in California from 1988 until about 2009 has declined and stabilized in recent years, signaling the end of a trend.
August 11, 2017
Julie Schweitzer, a professor in the Department of Psychiatry and Behavioral Sciences and UC Davis MIND Institute researcher, has received a $3.7 million grant from the National Institute of Mental Health (NIMH) to track impulsivity and self-control in teens and young adults over time.
July 31, 2017
Health plans that collaborated to share best practices and successful strategies for treating patients diagnosed with hypertension saw significant improvement in controlling high blood pressure, a study by the California Department of Health Care Services (DHCS) and UC Davis Institute of Population Health Improvement (IPHI) has found.
July 28, 2017
John Paul Aboubechara, a fifth-year student in the combined M.D./Ph.D. program at UC Davis School of Medicine, has been honored with this year’s Daniel T. O’Connor, M.D., Memorial Research Grant.
July 26, 2017
Sorting out when or whether to get mammograms can be perplexing for any woman, and a health provider’s advice may not settle the matter. That’s because even experts disagree about when screening mammography is appropriate and for whom.
July 25, 2017
The University of California has been awarded a nearly $14.7 million multi-year grant from the National Institutes of Health to study contributors to dementia in the Latino population in the United States. The multicenter study will examine the biological underpinnings of stroke, mild cognitive impairment and Alzheimer’s disease among Hispanics, and pursue new therapeutic directions to reduce brain health disparities.
July 24, 2017
The University of California Firearm Violence Research Center at UC Davis’ Sacramento campus officially launched July 4 under the direction of Garen Wintemute, a professor of emergency medicine and recognized authority on the epidemiology of firearm violence.
July 18, 2017
The results of an international clinical trial, led in part by a UC Davis School of Medicine expert, have shown that a drug therapy for a severe type of muscular dystrophy holds promise for a subgroup of patients.
July 14, 2017
The Society for Academic Emergency Medicine (SAEM) recently honored Nate Kuppermann with more than just a lifetime award for meritorious accomplishments in research and mentorship.
July 12, 2017
A new study published today in The American Journal of Pathologyfound that mice fed a high-fat, high-sugar Western diet developed hepatic inflammation, which was more common in males than females and most pronounced in mice that also lacked a bile acid receptor known as farnesoid x receptor, or FXR.
July 11, 2017
In a decisive move by the Governor and Legislature, the University of California Umbilical Cord Blood Collection Program (UCBCP) has been extended through 2022. The program enables mothers of newborns to donate their babies’ umbilical cord blood and have it publicly banked so it is available to anyone for lifesaving transplantations.
July 10, 2017
The Northern California chapter of Huntington’s Disease Society of American (HDSA) has honored UC Davis Health’s Lorin Scher for his outstanding service to the Huntington’s disease community in the Sacramento region.
June 28, 2017
UC Davis Health and the Sacramento City Fire Department have established a research partnership that aims to improve care for sick and injured children during and after an emergency transport.
June 22, 2017
Researchers at the UC Davis MIND Institute and Boston Children’s Hospital have confirmed that mice without the Shank3B protein model aspects of brain physiology and behavioral symptoms observed in people with autism. The findings confirm that Shank3B knockout mice provide a valuable research tool for future efforts to develop new therapies. The study, supported by Autism Speaks, was published in the journal Molecular Autism.
June 22, 2017
The survival rate of U.S. gunshot victims has not shown a marked improvement, as other recent studies have suggested, according to new research from Duke University and the University of California, Davis.
June 13, 2017
Despite evidence showing that the routine use of sonography in hospital emergency departments can safely improve care for adults when evaluating for possible abdominal trauma injuries, researchers at UC Davis Medical Center could not identify any significant improvements in care for pediatric trauma patients.
June 6, 2017
With its internationally renowned school of veterinary medicine and its NCI-designated comprehensive cancer center, UC Davis is uniquely positioned to harness the power of each to tackle one of life’s greatest challenges: cancer.
June 6, 2017
Researchers at UC Davis Health and other institutions have shown that gender differences in mice microbiota can modulate the risk of developing metabolic disease and liver cancer. In addition, the team found that a bile acid receptor protein, called FXR, has a profound impact on mouse microbiota and bile acid profiles and is differentially expressed based on gender. The study was published in the journal Scientific Reports.
May 24, 2017
UC Davis has signed a licensing agreement providing Isotropic Imaging Corporation the rights to commercialize a novel computed tomography (CT) scanner that has the potential to improve breast cancer detection and positively impact women’s health.
May 5, 2017
The UC Davis Neuromuscular Research Center has been recognized as a Certified Duchenne Care Center by Parent Project Muscular Dystrophy for national leadership in treating Duchenne muscular dystrophy.
April 26, 2017
Reducing by half the typical amount of blood provided through transfusions to burn patients makes no difference in terms of patient outcomes, a new multi-center study led by UC Davis researchers shows.
April 25, 2017
Patients in California hospitals were more likely to die within 60 days of being diagnosed with acute myeloid leukemia – a cancer of the blood and bone marrow – if they were unmarried, lived in a less-affluent neighborhood or lacked health insurance. The UC Davis study also found that patients treated at a National Cancer Institute (NCI)-designated cancer center were more likely to survive.
April 20, 2017
Second cancers in children and adolescents and young adults (AYA) are far deadlier than they are in older adults and may partially account for the relatively poor outcomes of cancer patients ages 15-39 overall, a new study by UC Davis researchers has found.
April 7, 2017
Adults with autism spectrum disorder (ASD) will be the topic of the next Minds behind the MIND lecture on April 19 at 5:30 p.m. at the UC Davis MIND Institute, 2825 50th St. in Sacramento. The lecture is free and open to the public.
March 23, 2017
In a new study published today in JCI Insight, UC Davis researchers have shown that combining high-intensity focused ultrasound with two immunotherapies (a PD-1 checkpoint inhibitor and TLR9 agonist) can produce excellent response rates in mouse models of epithelial cancer. They also found that, for the combination to be effective, immunotherapies must come first.
March 14, 2017
UC Davis emergency medicine researchers have been awarded a grant from the National Institutes of Health (National Heart, Lung, and Blood Institute) to investigate the safety and efficacy of a drug known to stop bleeding in injured adults for use in cases of pediatric trauma.
March 9, 2017
An international team of reseachers led by Thomas Borén at Umeå University and including Jay Solnick, professor internal medicine at UC Davis, has discovered the tmechanism that gives the bacteria such staying-power and ability to cause chronic infection.
March 7, 2017
With a $1 million grant from the National Science Foundation (NSF), UC Davis and Boston University will focus on establishing partnerships with industry, academe and government that lead to the development of innovative biophotonic technologies for use in medicine and other scientific disciplines.
University of California, Stanford partner on research to improve health in California and nationwide
March 7, 2017
The University of California Biomedical Research Acceleration, Integration, and Development program (UC BRAID) and Stanford University have formed an alliance to combine resources and develop a coordinated approach to research targeting the health of Californians – a partnership that can serve as a model for collaborations throughout the country.
UC Davis joins national consortium to find regenerative treatments for dental and craniofacial tissues
March 7, 2017
UC Davis will join other California research institutions in a three-year, $12 million effort to find regenerative treatments for dental, oral and craniofacial deformities and injuries.
March 6, 2017
Disagreements between doctors and patients over the priorities of pain treatment are common during primary care office visits, new research from UC Davis Health shows. Patients hope to reduce pain intensity and identify the cause, while physicians aim to improve physical function and reduce medication side effects, including dependency.
March 6, 2017
Researchers from the UC Davis MIND Institute, University of North Carolina (UNC) and other institutions have found that altered distribution of cerebrospinal fluid (CSF) in high-risk infants can predict whether they will develop autism spectrum disorder (ASD). The study appears today in the journal Biological Psychiatry.
UC Davis computational molecular biologist named Sloan fellow to study genetic causes of complex disorders
February 27, 2017
Fereydoun Hormozdiari, an early-career UC Davis scientist, has been named a 2017 Alfred P. Sloan Research Fellow in Computational & Evolutionary Molecular Biology. He is one of 126 scholars to receive the prestigious award, which comes with $60,000 over two years to conduct leading-edge research.
February 23, 2017
Researchers at UC Davis have received $3.2 million in federal funds to further investigate how obesity and inflammation affect the body’s immune system in fighting cancer.
February 21, 2017
In two recent studies, researchers at UC Davis have shown that the placenta can provide critical information about early changes to the intra-uterine environment that may influence fetal development and ultimately, children’s brains.
February 10, 2017
Language barriers may hinder U.S. kidney transplant candidates’ access to kidney transplantation, according to a new study in the Clinical Journal of the American Society of Nephrology. Led by a team from Cedars-Sinai, UCLA Health and UC Davis Health, the research suggests that patients who primarily speak a language other than English may face disparities that keep them from completing their kidney transplant evaluations and, ultimately, from receiving a transplant.
February 9, 2017
Older adults who live in poor and violent urban neighborhoods are at greater risk for depression, a study by researchers from UC Davis, the University of Minnesota and other institutions published Jan. 23 in the journal Health & Place has found.
February 7, 2017
UC Davis physician researchers have found that medical marijuana contains multiple bacterial and fungal pathogens that may cause serious and even fatal infections. They warn that smoking, vaping or inhaling aerosolized marijuana could pose a grave risk to patients, especially those with leukemia, lymphoma, AIDS or conditions requiring immune-suppressing therapies.